TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins

Ju Shi, Eileen L. Rose, Andrew Singh, Sami Hussain, Nancy E. Stagliano, Graham C. Parry, and Sandip Panicker

J Shi, EL Rose, A Singh, S Hussain… - 2014 -

Here we test the effects of TNT003, amouse monoclonal antibody targeting the CP-specific serine protease C1s, on CP activity induced by cold agglutininson human RBCs.

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