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Mobilized Peripheral Blood Mononuclear Cells

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These mononuclear cells (MNC) are collected using the Spectra Optia® Apheresis System (>90% of the cells are MNC). These MPB-MNC products have been depleted of red blood cells and platelets.
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Overview

Additional Information

These mononuclear cells (MNC) are collected using the Spectra Optia® Apheresis System (>90% of the cells are MNC). These MPB-MNC products have been depleted of red blood cells and platelets.

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Donor Criteria

Age18-40 years old
Weight140-280 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation Frequency
  • Minimum 12 months between donations
  • 2x lifetime donation maximum
Donors with any of the following will be excluded from donatingPregnancy
History of heart, lung, liver, or kidney disease
History of asthma
Blood and bleeding disorders including sickle cell disease
Neurologic disorders
Autoimmune disorders
Cancer
Diabetes
Other Criteria
  • Must be in general good health
  • Must have adequate peripheral veins
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Applications/Publications

Applications

  • Drug Screening
  • Toxicity or Immunogenicity Testing
  • Reagent validation

To Study

  • Everything

Related Bioservices

  • Th cell generation
  • T cell Proliferation analysis

Publications

Granulocyte colony-stimulating factor mobilized CFU-F can be found in the peripheral blood but have limited expansion potential

Troy C. Lund, et al.
Source: haematologica
Documentation

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