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Mobilized Peripheral Blood CD34+ Stem/Progenitor Cells

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 MPB-CD34+ Stem/Progenitor cells are positively selected using a direct immunomagnetic CD34 MicroBead labeling system.
Contact Us: Mon-Fri 7:30am to 6:00pm PST    510.726.2700    orders@allcells.com
ItemLegacy Catalog #FormatSizePriceQuantity 
mLP, RegF, CR, CD34+, PS, 0.5MmPB014FCryopreserved0.5 million
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mLP, RegF, CR, CD34+, PS, 1MmPB015FCryopreserved1 million
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mLP, RegF, FR, CD34+, PS, 1MmPB009Fresh1 million
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mLP, RegF, CR, CD34+, PS, 5MmPB016FCryopreserved5 million
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mLP, RegF, FR, CD34+, PS, 5MmPB010Fresh5 million
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mLP, RegF, CR, CD34+, PS, 10MmPB017FCryopreserved10 million
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mLP, RegF, FR, CD34+, PS, 10MmPB011Fresh10 million
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mLP, RegF, CR, CD34+, PS, 25MmPB018FCryopreserved25 million
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mLP, RegF, FR, CD34+, PS, 25MmPB012Fresh25 million
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Overview

Additional Information

 MPB-CD34+ Stem/Progenitor cells are positively selected using a direct immunomagnetic CD34 MicroBead labeling system.

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Donor Criteria

Age18-40 years old
Weight140-280 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation Frequency
  • Minimum 12 months between donations
  • 2x lifetime donation maximum
Donors with any of the following will be excluded from donatingPregnancy
History of heart, lung, liver, or kidney disease
History of asthma
Blood and bleeding disorders including sickle cell disease
Neurologic disorders
Autoimmune disorders
Cancer
Diabetes
Other Criteria
  • Must be in general good health
  • Must have adequate peripheral veins
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Applications/Publications

Applications

  • Drug Screening
  • Toxicity or Immunogenicity Testing
  • Reagent validation
  • Colony-forming (CFU) assays
  • Humanized mice generation

To Study

  • Stem cell expansion, lineage-commitment, and transplantation

Publications

Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells

Mark A. DeWitt, Wendy Magis, Nicolas L. Bray, Tianjiao Wang, Jennifer R. Berman, Fabrizia Urbinati, Seok-Jin Heo, Therese Mitros, Denise P. Muñoz, Dario Boffelli, Donald B. Kohn, Mark C. Walters, Dana Carroll, David I. Martin, Jacob E. Corn
Source: Science Translational Medicine. 8, 360ra134 (2016) 12 October 2016

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Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

Ayal Hendel, Rasmus O Bak, Joseph T Clark, Andrew B Kennedy, Daniel E Ryan, Subhadeep Roy, Israel Steinfeld, Benjamin D Lunstad, Robert J Kaiser, Alec B Wilkens, Rosa Bacchetta, Anya Tsalenko, Douglas Dellinger, Laurakay Bruhn & Matthew H Porteus
Source: Nature Biotechnology 33, 985–989 (2015), Published online 29 June 2015

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Transcriptional profiling of erythroid progenitors from G-CSF mobilized and nonmobilized peripheral blood

Vladan P. Cokic1, Milos Diklic1, Tijana Suboticki1, Bojana B. Beleslin-Cokic2, Dragana Markovic1, Pavle Milenkovic1, Gordana Jovcic1
Source: JBUON 2014; 19(1): 304-314 ISSN: 1107-0625, online ISSN: 2241-6293 • www.jbuon.com

An image-based screen identifies a small molecule regulator of megakaryopoiesis

Anthony E. Boitanoa, et al.
Source: PNAS | August 28, 2012 | vol. 109 | no. 35 | 14019–14023

Globin gene expression in correlation with G protein-related genes during erythroid differentiation

Vladan P Čokić, et al.
Source: BMC Genomics 2013, 14:116

Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice

Gene-Errol E. Ringpis, et al.
Source: PLoS ONE 7(12): e53492 December 31, 2012

Combined Characterization of microRNA and mRNA Profiles Delineates Early Differentiation Pathways of CD1331 and CD341 Hematopoietic Stem and Progenitor Cells

UTE BISSELS, et al.
Source: STEM CELLS Volume 29, Issue 5, pages 847–857, May 2011

A novel potent Fas agonist for selective depletion of tumor cells in hematopoietic transplants

A Nahimana, et al.
Source: Blood Cancer Journal (2011) 1, e47; doi:10.1038/bcj.2011.47

EFFECTS OF HIV-1 GP120 AND PROTEASE INHIBITORS ON APOPTOTIC SUSCEPTIBILITY OF CD34+ HEMATOPOIETIC PROGENITOR CELLS

Owen J MacEneaney, et al.
Source: J Acquir Immune Defic Syndr. 2011 February 1; 56(2): e49–e50. doi:10.1097/QAI.0b013e3181fb1cb3.

NF-Y Recruits Both Transcription Activator and Repressor to Modulate Tissue- and Developmental Stage-Specific Expression of Human c-Globin Gene

Xingguo Zhu, et al.
Source: PLoS ONE 7(10): e47175. doi:10.1371/journal.pone.0047175 October 10, 2012

RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes

David YOWE, et al.
Source: Biochem. J. (2001) 359, 109±118 (Printed in Great Britain)

Loss of Specific Chaperones Involved in Membrane Glycoprotein Biosynthesis during the Maturation of Human Erythroid Progenitor Cells

Sian T. Patterson, et al.
Source: THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 284, NO. 21, pp. 14547–14557, May 22, 2009

Generation of induced pluripotent stem cells from human blood

Yuin-Han Loh, et al.
Source: Blood First Edition Paper, prepublished online March 18, 2009; DOI 10.1182/blood-2009-02-204800
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