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Acute Lymphoid Leukemia (ALL)
Diseased Peripheral Blood MNC

Availability: Out of stock

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Catalog # : ALL-PB001F

PB-MNC are isolated from ALL peripheral blood by diluting the whole blood with PBS and using gradient separation techniques.  After centrifugation, the mononuclear cell layer is collected. MNC can be processed further to isolate subpopulations. ALL-MNC are available in the newly diagnosed and relapsed/refractory stages.
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Item #FormatDisease StageProduct nameSizePriceQuantity 
ALL-PB001F CryopreservedTreatment Naive Mononuclear Cells (MNC) 10 million

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Overview

Additional Information

PB-MNC are isolated from ALL peripheral blood by diluting the whole blood with PBS and using gradient separation techniques.  After centrifugation, the mononuclear cell layer is collected. MNC can be processed further to isolate subpopulations. ALL-MNC are available in the newly diagnosed and relapsed/refractory stages.

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Donor Criteria

Age+18 years old
Weight>= 110 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation FrequencyMinimum 10 weeks between donations
Donors with any of the following will be excluded from donating
  • Pregnancy
  • Active or serious acute or chronic infection requiring continued management
  • Serious pulmonary or cardiovascular disease or condition
Other Criteria
  • Other health conditions at discretion of donor's physician
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Storage & Shipping

CRYOPRESERVED CELL STORAGE
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Applications/Publications

Applications

  • Drug Screening
  • Toxicity or Immunogenicity Testing
  • Reagent validation

To Study

  • Everything

Related Bioservices

  • Th cell generation
  • T cell Proliferation analysis

Publications

Agonist antibody that induces human malignant cells to kill one another

Kyungmoo Yeaa , Hongkai Zhangb , Jia Xieb , Teresa M. Jonesb , Chih-Wei Linb , Walter Francesconic , Fulvia Bertond , Mohammad Fallahie , Karsten Sauerb,f, and Richard A. Lernerb
Source: Proceedings of the National Academy of Sciences of the United States of America, Contributed by Richard A. Lerner, September 25, 2015

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A novel antibody–drug conjugate targeting SAIL for the treatment of hematologic malignancies

SY Kim , J-W Theunissen , J Balibalos , S Liao-Chan , MC Babcock , T Wong , B Cairns , D Gonzalez , EH van der Horst , M Perez , Z Levashova , L Chinn , JA D‘Alessio , M Flory , A Bermudez , DY Jackson , E Ha , J Monteon , MF Bruhns , G Chen, and T-S Migone
Source: Citation: Blood Cancer Journal (2015) 5, e316; doi:10.1038/bcj.2015.39 Published online 29 May 2015

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Potential Small Guide RNAs for tRNase ZL from Human Plasma, Peripheral Blood Mononuclear Cells, and Cultured Cell Lines

Sho Ninomiya , Mitsuoki Kawano, Takashi Abe , Tatsuya Ishikawa , Masayuki Takahashi , Masato Tamura , Yoshiaki Takahashi , Masayuki Nashimoto
Source: PLoS ONE Published March 2, 2015

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A phase 1b/2 study of combination vosaroxin and cytarabine in patients with relapsed or refractory acute myeloid leukemia

Jeffrey E. Lancet, Gail J. Roboz, Larry D. Cripe, Glenn C. Michelson, Judith A. Fox, Richard D. Leavitt, Tianling Chen, Rachael Hawtin, Adam R. Craig, Farhad Ravandi, Michael B. Maris, Robert K. Stuart, and Judith E. Karp
Source: Haematologica. 2014; 99:xxx doi:10.3324/haematol.2014.114769

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Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia

S Hart, et al.
Source: Blood Cancer Journal (2011) 1, e44; doi:10.1038/bcj.2011.43 Published online 11 November 2011

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