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Acute Myeloid Leukemia (AML)
Diseased Bone Marrow CD34+ Stem/Progenitor Cells

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AML-BM-CD34+ cells are selected from adult AML-BM-MNC. The BM-CD34+ stem/progenitor cells are positively isolated using a direct immunomagnetic CD34 MicroBead labeling system. AMLCD34+ cells are available in the newly diagnosed and relapsed/ refractory stages.
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AML-BM-CD34+ cells are selected from adult AML-BM-MNC. The BM-CD34+ stem/progenitor cells are positively isolated using a direct immunomagnetic CD34 MicroBead labeling system. AMLCD34+ cells are available in the newly diagnosed and relapsed/ refractory stages.

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Donor Criteria

Age+18 years old
Weight>= 110 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation FrequencyMinimum 10 weeks between donations
Donors with any of the following will be excluded from donating
  • Pregnancy
  • Active or serious acute or chronic infection requiring continued management
  • Serious pulmonary or cardiovascular disease or condition
Other Criteria
  • Other health conditions at discretion of donor's physician
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Applications/Publications

Applications

  • Drug Screening
  • Toxicity or Immunogenicity Testing
  • Reagent validation
  • Colony-forming (CFU) assays
  • Humanized mice generation

To Study

  • Stem cell expansion, lineage-commitment, and transplantation
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