750

Acute Lymphoid Leukemia (ALL)
Diseased Bone Marrow CD19+ B Cells

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Catalog # : ALL-B012F-0

ALL-BM-CD19+ B cells are positively isolated from adult ALL-BMMNC, using a direct immunomagnetic CD19 MicroBead labeling system. These CD19+ B cells are are available in newly diagnosed and relapsed/refractory stages.
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Catalog #FormatDisease StageProduct nameSizePriceQuantity 
ALL-B012FCryopreservedTreatment Naive Diseased Bone Marrow CD19+ B Cells5 million
ALL-B013FCryopreservedTreatment Naive Diseased Bone Marrow CD19+ B Cells10 million

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Overview

Additional Information

ALL-BM-CD19+ B cells are positively isolated from adult ALL-BMMNC, using a direct immunomagnetic CD19 MicroBead labeling system. These CD19+ B cells are are available in newly diagnosed and relapsed/refractory stages.

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Donor Criteria

Age+18 years old
Weight>= 110 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation FrequencyMinimum 10 weeks between donations
Donors with any of the following will be excluded from donating
  • Pregnancy
  • Active or serious acute or chronic infection requiring continued management
  • Serious pulmonary or cardiovascular disease or condition
Other Criteria
  • Other health conditions at discretion of donor's physician
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Storage & Shipping

CRYOPRESERVED CELL STORAGE
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SHIPPING
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Applications/Publications

Applications

  • Generating antibody libraries
  • Co-culture with T helper cells or cytotoxic lymphocytes (CTL)

To Study

  • B cell activation, clonal expansion, Ig rearrangement, and Ig secretion
  • Antigen presenting cell (APC) signal transduction and antigen presentation
  • Antigen presenting cell (APC) signal transduction and antigen presentation

Publications

Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity

Anita K. Gandhi, Derek Mendy, Michelle Waldman, Gengxin Chen, Emily Rychak, Karen Miller, Svetlana Gaidarova, Yan Ren, Maria Wang, Michael Breider, Gilles Carmel, Afshin Mahmoudi, Pilgrim Jackson, Mahan Abbasian, Brian E. Cathers, Peter H. Schafer, Tom O. Daniel, Antonia Lopez-Girona, Anjan Thakurta andRajesh Chopra
Source: British Journal of Haematology Volume 164, Issue 2, pages 233–244, January 2014

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Video & Technical Resources
Documentation

Product Attachments

Certificate of Analysis Sample - Frozen

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