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Bone Marrow CD34+ Stem/Progenitor Cells

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BM-CD34+ stem/progenitor cells are positively isolated using a direct immunomagnetic CD34 MicroBead labeling system.
Contact Us: Mon-Fri 7:30am to 6:00pm PST    510.726.2700    orders@allcells.com
ItemLegacy Catalog #FormatSizePriceQuantity 
BM, CR, CD34+, PS, 0.25MABM021FCryopreserved0.25 million
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BM, CR, CD34+, PS, 0.5MABM022FCryopreserved0.5 million
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BM, FR, CD34+, PS, 0.5MABM011Fresh0.5 million
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BM, CR, CD34+, PS, 1MABM017FCryopreserved1 million
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BM, FR, CD34+, PS, 1MABM012Fresh1 million
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Overview

Additional Information

BM-CD34+ stem/progenitor cells are positively isolated using a direct immunomagnetic CD34 MicroBead labeling system.

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Donor Criteria

Age18-65 years old
Weight>= 130 lbs
Screened before donation
  • HIV (HIV 1 & 2 Ab)
  • HBV (Surface Antigen HbsAg)
  • HCV (HCVAb)
Donation FrequencyMinimum 10 weeks between donations
Donors with any of the following will be excluded from donatingPregnancy
History of heart, lung, liver, or kidney disease
History of asthma
Blood and bleeding disorders including sickle cell disease
Neurologic disorders
Autoimmune disorders
Cancer
Diabetes
Other Criteria
  • Must be in general good health
  • Must have accessible hips
  • Complete Blood Count lab test must meet protocol specs
  • Required to sign procedure-specific consent form

Applications/Publications

Applications

  • Drug Screening
  • Toxicity or Immunogenicity Testing
  • Reagent validation
  • Colony-forming (CFU) assays
  • Humanized mice generation

To Study

  • Stem cell expansion, lineage-commitment, and transplantation

Publications

Suppression of cancer relapse and metastasis by inhibiting cancer stemness

Youzhi Li, Harry A. Rogoff, Sarah Keates, Yuan Gao, Sylaja Murikipudi, Keith Mikule, David Leggett, Wei Li, Arthur B. Pardee, and Chiang J. Li
Source: PNAS | February 10, 2015 | vol. 112 | no. 6 | 1839–1844

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Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias

Yunyi Kang, Andrew Hodges, Edison Ong, William Roberts, Carlo Piermarocchi, Giovanni Paternostro
Source: PLoS ONE Published July 16, 2014

Proteomic Profiling Identifies Distinct Protein Patterns in Acute Myelogenous Leukemia CD34+CD38- Stem-Like Cells

Kornblau SM, Qutub A, Yao H, York H, Qiu YH, et al.
Source: PLoS ONE 8(10): e78453. doi:10.1371/journal.pone.0078453 Published October 24, 2013

Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias

Yunyi Kang, Andrew Hodges, Edison Ong, William Roberts, Carlo Piermarocchi, Giovanni Paternostro
Source: PLoS ONE 9(7): e102221. doi:10.1371/journal.pone.0102221

miR-21 mediates hematopoietic suppression in MDS by activating TGF-b signaling

Cy Stein, et al.
Source: BLOOD, 121: 2875-2881: 11 APRIL 2013

Growth Factor-Activated Stem Cell Circuits and Stromal Signals Cooperatively Accelerate Non-Integrated iPSC Reprogramming of Human Myeloid Progenitors

Tea Soon Park, et al.
Source: PLoS ONE 7(8): e42838. doi:10.1371/journal.pone.0042838 August 8, 2012

Human Cardiac Stem Cells Isolated from Atrial Appendages Stably Express c-kit

Jia-Qiang He, et al.
Source: PLoS ONE 6(11): e27719. doi:10.1371/journal.pone.0027719 November 2 , 2011

Bone Marrow Osteoblast Damage by Chemotherapeutic Agents

Stephanie L. Rellick,et al.
Source: PLoS ONE 7(2): e30758. doi:10.1371/journal.pone.0030758 February 17, 2012

Reduced SMAD7 Leads to Overactivation of TGF-b Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF b Receptor I Kinase

Li Zhou, et al.
Source: Cancer Res February 1, 2011 71;955

SALL4 is a robust stimulator for the expansion of hematopoietic stem cells

Jerell R. Aguila, et al.
Source: Blood July 21, 2011 vol. 118 no. 3 576-585

A novel potent Fas agonist for selective depletion of tumor cells in hematopoietic transplants

A Nahimana, et al.
Source: Blood Cancer Journal (2011) 1, e47; doi:10.1038/bcj.2011.47

JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

Vladan P Cokic, et al.
Source: Cokic et al. Journal of Translational Medicine 2012, 10:116

Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells

Xinqiang Huang, et al.
Source: February 17, 2011 vol. 117 no. 7 2157-2165

Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias

Judith E. Karp, et al.
Source: Blood March 24, 2011 vol. 117 no. 12 3302-3310

Anovel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor

Tetsuro Orita, et al.
Source: BLOOD, 15 JANUARY 2005  VOLUME 105, NUMBER 2

AMAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNAtranslation

Mario Notari, et al.
Source: BLOOD, 15 MARCH 2006  VOLUME 107, NUMBER 6

The Minimal Instrumentation Requirements for Hoechst Side Population Analysis: Stem Cell Analysis on Low-Cost Flow Cytometry Platforms

RAQUEL CABANA, et al.
Source: STEMCELLS 2006;24:2573–2581

RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes

David YOWE, et al.
Source: Biochem. J. (2001) 359, 109±118 (Printed in Great Britain)

Local gene density predicts the spatial position of genetic loci in the interphase nucleus

A.E. Murmann et al
Source: Experimental Cell Research 311 (2005) 14– 26

Human skin cells support thymus-independent T cell development

Rachael A. Clark, et al.
Source: J. Clin. Invest. 115:3239–3249 (2005). doi:10.1172/JCI24731.
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