AllCells has isolated mononuclear cells from the peripheral blood of Type I Diabetic patients. In addition plasma collects are also available. Treatment history of each patient is available.
The following Diabetic Type I cells and tissue product types are available from AllCells:
Fresh/Frozen Type I Diabetic Peripheral Blood Mononuclear Cells (DIA1 PB MNC)
Fresh/Frozen Type I Diabetic Peripheral Blood Plasma
Fresh Type I Diabetic Peripheral Blood*
*available upon request
Donor Criteria & Screening
Type I Diabetic cells and tissue products are obtained from volunteers participating in an Institutional Review Board (IRB) or Human Subject Committee approved donor program. All donors sign an informed consent form and are aware that these cells are used for research purposes. Donors must be over the age of 18.
See our entire Type I Diabetic cells product listing below.
Diabetes Type I also referred to as Diabetes Mellitus Type I (formally juvenile diabetes), results from autoimmune destruction of insulin-producing beta cells of the pancreas. The subsequent lack of insulin leads to an increase of blood and urine glucose.
Eventually Type I Diabetes is fatal unless treated with insulin. Pancreatic transplants have been used to replenish a natural supply of insulin. Pancreatic islet cell transplantation is experimental though more procedures are occurring annually.
Type I Diabetes is a polygenic disease. Depending on locus or combination of loci, it can be dominant, recessive, or somewhere in-between. The strongest gene, IDDM1, is located in the MHC Class II region on chromosome 6 at staining region 6p21.
The appearance of Diabetes-related autoantibodies has been shown to be able to predict the appearance of Diabetes Type I before any hyperglycemia occurs.
Diabetes Type I specimens can be used in preclinical research, drug discovery, drug toxicity, biomarker development, and pre-selection of indication for clinical trials.