Mobilized Peripheral Blood

Background

Granulocyte-Colony Stimulating Factor (G-CSF) can stimulate bone marrow to produce a large number of hematopoietic stem/progenitor cells. G-CSF can mobilize these stem/progenitor cells from bone marrow into the peripherablood stream.

The effects of G-CSF have changed the practice of bone marrow transplantation. Consequently, mobilized peripheral blood cells (MPB) have become major sources for clinical hematopoietic stem cell transplantation.

AllCells is the only provider of Mobilized Peripheral Blood in the world.

DONOR CRITERIA

• Age: 18-40 years old
• Weight: >140 lbs
• CBC lab tests must meet protocol specifications
• Donors cannot be pregnant.
• Donors are screened for HIV, Hepatitis B and Hepatitis C before donation.
  Donors must be in general good health. Donors with any of the following will be excluded from donating:
  • History of heart, lung, liver, kidney disease (including asthma)
  • Blood and bleeding disorders, including sickle cell disease
  • Neurologic disorders
  • Cancer
  • Diabetes
  • Positive: HIV, HbsAg, HCAb
• Donors must have adequate peripheral veins for apheresis.
• Donors are required to sign a procedure-specific consent form prior to the collection procedure