Mouse Spleen

Background

First, the mouse spleen is dissociated into a single cell suspension. Next, the spenocytes are enriched by density separation. The rat splenocytes can be used to isolate CD4⁺ T cells, CD8⁺ T cells, and CD19⁺ B cells using specific immunomagnetic methods.

Mouse Splenocytes can be used to study:

- Growth factor and cytokine release from lymphocytes as well as monocytes and Kupffer cells

- Function and mechanism of normal and diseased models in the reticuloendothelial system

-  Homing and processing of red blood cells

-  Antigen-recognition conditioning and proliferation of lymphocytes and monoctyes