AllCells has isolated mononuclear cells from the peripheral blood of SLE patients. In addition plasma collects are also available. Medical history of each patient is available and may include treatment history, ANA analysis, and SLEDAI score.
The following Systemic Lupus Erythematosus cells and tissue product types are available from AllCells:
Lupus cells and tissue products are obtained from volunteers participating in an Institutional Review Board (IRB) or Human Subject Committee approved donor program. All donors sign an informed consent form and are aware that these cells are used for research purposes. Donors must be over the age of 18.
See below for our entire SLE cells product listing.
Systemic Lupus Erythematosus (SLE) is a Type III Hypersensitivity Reaction caused by an antibody immune complex formation. Often referred to as 'lupus', SLE is a systemic autoimmune disease that can affect any part of the body.
SLE is treatable using immunosuppression, mainly with cyclophosphamide, corticosteroids, and other immunosuppressants. There is currently no cure for SLE. SLE can be fatal although with recent medical advances, fatalities are becoming increasingly rare. Survival for people with SLE in the United States and Canada has risen to approximately 95% at 5 years, 90% at 10 years, and 78% at 20 years.
Antinuclear antibody testing (ANA) and anti-extractable nuclear antigen (anti-ENA) are the mainstay of serologic testing for SLE. Other tests routinely performed in suspected SLE diagnosis are compliment system levels, electrolytes and renal function, liver enzymes, and complete blood count.
SLE specimens can be used in preclinical research, drug discovery, drug toxicity, biomarker development, and pre-selection of indication for clinical trials.