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Mobilized Peripheral Blood

Mobilized Peripheral Blood

AllCells has been a pioneer in the use of G-CSF stimulation in normal healthy donors since 1998. The protocols in use for our Mobilized Peripheral Blood (MPB) products have been approved by an IRB and are overseen by clinical physicians. In addition all donors are monitored during the injection, collection procedure and post-collection to ensure the health of our donors is a priority.

AllCells is one of only a few providers of Mobilized Peripheral Blood in the world.

AllCells features the following Mobilized Peripheral Blood (MPB) products:

  • Fresh Mobilized Leuko Pak – Apheresis Collection (One-Day, Two-Day)
  • Fresh/Frozen MPB CD14+ Monocytes
  • Fresh/Frozen MPB Mononuclear Cells (MNC)
  • Fresh/Frozen MPB CD56+ Natural Killer (NK) Cells
  • Fresh/Frozen MPB CD34+ Stem/Progenitor Cells
  • Fresh/Frozen MPB CD133+ Stem/Progenitor Cells
  • Frozen MPB CD34 Depleted Mononuclear Cells (MNC)
  • Molecular Products (RNA and cDNA) for all MPB Products

See our entire inventory of Mobilized Peripheral Blood products below.

Background


Granulocyte-Colony Stimulating Factor (G-CSF) can stimulate bone marrow to produce a large number of hematopoietic stem/progenitor cells. G-CSF can mobilize these stem/progenitor cells from bone marrow into the peripheral blood stream.

The effects of G-CSF have changed the practice of bone marrow transplantation. Consequently, mobilized peripheral blood cells have become major sources for clinical hematopoietic stem cell transplantation.

Donor Criteria

  • Age: 18-40 years old
  • Weight: >140 lbs
  • CBC lab tests must meet protocol specifications
  • Donors cannot be pregnant.
  • Donors are screened for Antibodies against HIV 1 & 2 (HIV 1 & 2 Ab), Hepatitis B Surface Antigen (HbsAg) and Antibody against HCV ( HCVAb)
  • Donors must be in general good health. Donors with any of the following will be excluded from donating:
    • History of heart, lung, liver, kidney disease (including asthma)
    • Blood and bleeding disorders, including sickle cell disease
    • Neurologic disorders
    • Cancer
    • Diabetes
    • Positive tests for Antibodies against HIV 1 & 2 (HIV 1 & 2 Ab), Hepatitis B Surface Antigen (HbsAg) and Antibody against HCV ( HCVAb)
  • Donors must have adequate peripheral veins for apheresis.
  • Donors are required to sign a procedure-specific consent form prior to the collection procedure
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Mobilized Peripheral Blood

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  Catalog # Format Name Size Price Qty.
mPB025-Moz.A Fresh Fresh Mozobil-mobilized PB Leuko Pak; Mozobil @20mg/ml, 1.2ml single dose - Regimen A 1 Bag $34855
mPB025-Reg.E Fresh Fresh G-CSF-mobilized PB Leuko Pak; G-CSF @5ug/kg/day x 5days-Regimen E; apheresis on day 5 1 Bag $10321
RNA-mPB036C Comprehensive RNA Frozen Mobilized PB CD36+ Early Erythroid Progenitor Comprehensive RNA, 1.0ug 1.0 μg $481
mPB033F-3 Frozen Frozen Mobilized PB CD14+ Monocytes, 45 million 45 million $1321
mPB033F-2 Frozen Frozen Mobilized PB CD14+ Monocytes, 25 million 25 million $1076
mPB033-3 Fresh Fresh Mobilized PB CD14+ Monocytes, 45 million 45 million $1530
mPB033-2 Fresh Fresh Mobilized PB CD14+ Monocytes, 25 million 25 million $1123
RNA-mPB001C Comprehensive RNA Frozen Mobilized PB MNC Comprehensive RNA, 50.0ug 50.0 μg $481
RNA-mPB009C Comprehensive RNA Frozen Mobilized PB CD34+ Cells Comprehensive RNA, 1.0ug 1.0 μg $481
RNA-mPB010C Comprehensive RNA Frozen Mobilized PB CD133+ Cells Comprehensive RNA, 1.0ug 1.0 μg $879

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