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Mantle Cell Lymphoma (MCL)

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Background

Mantle Cell Lymphoma (MCL) is one of the rarer types of NHL. MCL is a disease of naïve pre-germinal center B cells, located in the “mantle zone” surrounding the normal germinal center follicles. A distinctive translocation at t(11;14)(q13;q32) causes upregulation of Bcl-1, development arrest, and unlimited proliferation of the mantle-zone B cells. This chromosomal translocation causes the over-expression of Bcl-1’s protein product, Cyclin-D1. In addition, these mantle-zone B cells express the CD5 marker. MCL is one of the few NHLs that can cross the blood-brain barrier.

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Mantle Cell Lymphoma (MCL)

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  Catalog # Format Name Size Price Qty.
MCL-B009F Frozen MCL Peripheral Blood CD19+ B Cells - Relapsed/Refractory 5 million $1109
$443.6
MCL-BM001F Frozen Frozen MCL BM MNC (Newly Diagnosed / Untreated), 10 million/vial 10 million $524/vial
$419.2/vial
MCL-BM003F Frozen Frozen MCL BM MNC (Relapsed / Refractory), 10 million/vial 10 million $582/vial
MCL-BM011F Frozen Frozen MCL BM Plasma (Newly Diagnosed / Untreated), 5 ml/vial 5 ml $115/vial
MCL-BM012F Frozen Frozen MCL BM Plasma (Relapsed / Refractory), 5 ml/vial 5 ml $115/vial
MCL-PB001F Frozen Frozen MCL PB MNC (Newly Diagnosed / Untreated), 10 million/vial 10 million $524/vial
$419.2/vial
MCL-PB003F Frozen Frozen MCL PB MNC (Relapsed / Refactory), 10 million/vial 10 million $582/vial
$465.6/vial
MCL-PB005F Frozen MCL Peripheral Blood Mononuclear Cells - Relapsed/Refractory 100 million $4431
$1772.4
MCL-PB011F Frozen Frozen MCL PB Plasma (Newly Diagnosed / Untreated), 5 ml/vial 5 ml $115/vial
MCL-PB012F Frozen Frozen MCL PB Plasma (Relapsed / Refractory), 5 ml/vial 5 ml $115/vial

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